Author's response to reviews Title: Genomic profiling identifies common HPV-associated chromosomal alterations in squamous cell carcinomas of cervix and head and neck Authors:
نویسندگان
چکیده
Saskia M Wilting ([email protected]) Serge J Smeets ([email protected]) Peter JF Snijders ([email protected]) Wessel N van Wieringen ([email protected]) Mark A van de Wiel ([email protected]) Gerrit A Meijer ([email protected]) Bauke Ylstra ([email protected]) C René Leemans ([email protected]) Chris JLM Meijer ([email protected]) Ruud H Brakenhoff ([email protected]) Boudewijn JM Braakhuis ([email protected]) Renske DM Steenbergen ([email protected])
منابع مشابه
Author's response to reviews Title: Gene-expression of metastasized versus non-metastasized primary head and neck squamous cell carcinomas: a pathway-based analysis Authors:
Title: Gene-expression of metastasized versus non-metastasized primary head and neck squamous cell carcinomas: a pathway-based analysis
متن کاملHuman papillomavirus type 16 in head and neck carcinogenesis.
The aetiology of squamous cell carcinomas of the head and neck (HNSCC) is multifactorial. Oncogenic human papillomaviruses (HPVs), a causative agent in uterine cervical cancer, have also been repeatedly detected in HNSCC, especially in squamous cell carcinomas of tonsils. Approximately half the HPV DNA-positive HNSCC contain detectable E6/E7 transcripts with wild-type p53, reduced pRb and overe...
متن کاملThe Prevalence of Human Papilloma Virus in Esopha-geal Squamous Cell Carcinoma
Background: Carcinomas of esophagus, mostly squamous cell carcinomas, occur throughout the world. There are a number of suspected genetic or environmental etiologies. Human papilloma virus (HPV) is said to be a major etiology in areas with high incidence of esophageal carcinoma, while it is hardly detectable in low incidence regions. This study was designed to evaluate the prevalence of HPV in ...
متن کاملIncidence of Etiologic Factors in Squamous Cell Carcinoma of Head and Neck in Ahvaz
Introduction: Squamous cell carcinoma (SCC) is the most common head and neck malignancy. Smoking, alcohol consumption, viral infections, exposure, oral hygiene, and dietary, genetic, and occupational factors are the most important etiologic factors. The aim of this study was determining the incidence of etiologic factors in head and neck SCC. Materials and Methods: This is a cross-sectiona...
متن کاملHuman Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx.
Purpose In squamous cell carcinomas of the head and neck (HNSCC), the increasing incidence of oropharyngeal squamous cell carcinomas (OPSCCs) is attributable to human papillomavirus (HPV) infection. Despite commonly presenting at late stage, HPV-driven OPSCCs are associated with improved prognosis compared with HPV-negative disease. HPV DNA is also detectable in nonoropharyngeal (non-OPSCC), bu...
متن کامل